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A transcription-centric model of SNP-age interaction
Complex age-associated phenotypes are caused, in part, by an interaction between an individual’s genotype and age. The mechanisms governing such interactions are however not entirely understood. Here, we provide a novel transcriptional mechanism-based framework–SNiPage, to investigate such interacti...
Autores principales: | Wang, Kun, Basu, Mahashweta, Malin, Justin, Hannenhalli, Sridhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997000/ https://www.ncbi.nlm.nih.gov/pubmed/33770080 http://dx.doi.org/10.1371/journal.pgen.1009427 |
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