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GM-1111 reduces radiation-induced oral mucositis in mice by targeting pattern recognition receptor-mediated inflammatory signaling

PURPOSE: Oral mucositis (OM) is a common, painful side effect of radiation therapy used for the treatment of head and neck cancer (HNC). Activation of the innate immune system upon irradiation has been identified as a key precipitating event of OM. To better understand OM’s pathogenesis, we studied...

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Detalles Bibliográficos
Autores principales:	Pulsipher, Abigail, Savage, Justin R., Kennedy, Thomas P., Gupta, Kavita, Cuiffo, Benjamin G., Sonis, Stephen T., Lee, Won Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997003/ https://www.ncbi.nlm.nih.gov/pubmed/33770116 http://dx.doi.org/10.1371/journal.pone.0249343

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