Cargando…

Substrate Activation of the Low-Molecular Weight Protein Tyrosine Phosphatase from Mycobacterium tuberculosis

[Image: see text] Mycobacterium tuberculosis is known to express a low-molecular weight protein tyrosine phosphatase. This enzyme, denoted as MptpA (Mycobacterium protein tyrosine phosphatase A), is essential for the pathogen to escape the host immune system and therefore represents a target for the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stefan, Alessandra, Dal Piaz, Fabrizio, Girella, Antonio, Hochkoeppler, Alejandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997110/ https://www.ncbi.nlm.nih.gov/pubmed/32142609 http://dx.doi.org/10.1021/acs.biochem.0c00059

Ejemplares similares

Shikonin and Juglone Inhibit Mycobacterium tuberculosis Low-Molecular-Weight Protein Tyrosine Phosphatase a (Mt-PTPa)
por: Sulyman, Abdulhakeem O., et al.
Publicado: (2023)

Production in Escherichia coli of recombinant COVID-19 spike protein fragments fused to CRM197
por: Bellone, Maria Laura, et al.
Publicado: (2021)

High-yield production in Escherichia coli and convenient purification of a candidate vaccine against SARS-CoV-2
por: Maltoni, Giulia, et al.
Publicado: (2022)

Diabetes reversal by inhibition of the low molecular weight tyrosine phosphatase
por: Stanford, Stephanie M, et al.
Publicado: (2017)

The DnaE polymerase from Deinococcus radiodurans features RecA-dependent DNA polymerase activity
por: Randi, Lorenzo, et al.
Publicado: (2016)

Dual role of imidazole as activator/inhibitor of sweet almond (Prunus dulcis) β-glucosidase
por: Caramia, Sara, et al.
Publicado: (2017)

Therapeutic Targeting of Protein Tyrosine Phosphatases from Mycobacterium tuberculosis
por: Ruddraraju, Kasi Viswanatharaju, et al.
Publicado: (2020)

Activation of the Low Molecular Weight Protein Tyrosine Phosphatase in Keratinocytes Exposed to Hyperosmotic Stress
por: Silva, Rodrigo A., et al.
Publicado: (2015)

Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (PtpB) Inhibitors from Natural Products
por: Mascarello, Alessandra, et al.
Publicado: (2013)

Low molecular weight protein phosphatase APH mediates tyrosine dephosphorylation and ABA response in Arabidopsis.
por: Du, Yanyan, et al.
Publicado: (2022)

The functional interplay of low molecular weight thiols in Mycobacterium tuberculosis
por: Sao Emani, C., et al.
Publicado: (2018)

Low molecular weight protein tyrosine phosphatase (LMWPTP) upregulation mediates malignant potential in colorectal cancer
por: Hoekstra, Elmer, et al.
Publicado: (2015)

Characterization of New Substrates Targeted By Yersinia Tyrosine Phosphatase YopH
por: de la Puerta, María Luisa, et al.
Publicado: (2009)

Deletion of low molecular weight protein tyrosine phosphatase (Acp1) protects against stress‐induced cardiomyopathy
por: Wade, Fallou, et al.
Publicado: (2015)

Structural and Biochemical Characterization of the Two Drosophila Low Molecular Weight-Protein Tyrosine Phosphatases DARP and Primo-1
por: Lee, Hye Seon, et al.
Publicado: (2020)

Inositol monophosphate phosphatase genes of Mycobacterium tuberculosis
por: Movahedzadeh, Farahnaz, et al.
Publicado: (2010)

Tyrosine phosphatase activity is restricted by basic charge substituting mutation of substrates
por: Huang, Che-Fan, et al.
Publicado: (2022)

Virtual Screening and Biological Evaluation of Novel Low Molecular Weight Protein Tyrosine Phosphatase Inhibitor for the Treatment of Insulin Resistance
por: Feng, Bo, et al.
Publicado: (2023)

Podocyte Protein, Nephrin, Is a Substrate of Protein Tyrosine Phosphatase 1B
por: Aoudjit, Lamine, et al.
Publicado: (2011)

The molecular clock of Mycobacterium tuberculosis
por: Menardo, Fabrizio, et al.
Publicado: (2019)

PSTPIP: A Tyrosine Phosphorylated Cleavage Furrow–associated Protein that Is a Substrate for a PEST Tyrosine Phosphatase
por: Spencer, Susan, et al.
Publicado: (1997)

Identification of protein tyrosine phosphatase 1B and casein as substrates for 124-v-Mos
por: Proikas-Cezanne, Tassula, et al.
Publicado: (2002)

Knocking Down Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP) Reverts Chemoresistance through Inactivation of Src and Bcr-Abl Proteins
por: Ferreira, Paula A., et al.
Publicado: (2012)

Inflammatory Bowel Disease: Are There Gender Differences in the Genetics of Signal Transduction? A Preliminary Study of Cytosolic Low Molecular Weight Protein Tyrosine Phosphatase
por: Bottini, Nunzio, et al.
Publicado: (2000)

Low Molecular Weight Protein Tyrosine Phosphatase Isoforms Regulate Breast Cancer Cells Migration through a RhoA Dependent Mechanism
por: Alho, Irina, et al.
Publicado: (2013)

Osteopontin inhibits osteoblast responsiveness through the down-regulation of focal adhesion kinase mediated by the induction of low–molecular weight protein tyrosine phosphatase
por: Kusuyama, Joji, et al.
Publicado: (2017)

Inhibition of the Low Molecular Weight Protein Tyrosine Phosphatase (LMPTP) as a Potential Therapeutic Strategy for Hepatic Progenitor Cells Lipotoxicity—Short Communication
por: Alicka, Michalina, et al.
Publicado: (2019)

Wzb of Vibrio vulnificus represents a new group of low-molecular-weight protein tyrosine phosphatases with a unique insertion in the W-loop
por: Wang, Xin, et al.
Publicado: (2021)

Determination of the molecular reach of the protein tyrosine phosphatase SHP-1
por: Clemens, Lara, et al.
Publicado: (2021)

Structural insights into mode of actions of novel natural Mycobacterium protein tyrosine phosphatase B inhibitors
por: Dhanjal, Jaspreet Kaur, et al.
Publicado: (2014)

Simple Tyrosine Derivatives Act as Low Molecular Weight Organogelators
por: Aykent, Güzide, et al.
Publicado: (2019)

Functional characterization of two members of histidine phosphatase superfamily in Mycobacterium tuberculosis
por: Coker, Olabisi Oluwabukola, et al.
Publicado: (2013)

Identification of New Substrates of the Protein-tyrosine Phosphatase PTP1B by Bayesian Integration of Proteome Evidence
por: Ferrari, Emanuela, et al.
Publicado: (2011)

Teaching an old dog new tricks: A new tool for protein tyrosine phosphatase substrate discovery
por: Bennett, Anton M.
Publicado: (2023)

Structural and catalytic insights into HoLaMa, a derivative of Klenow DNA polymerase lacking the proofreading domain
por: Kovermann, Michael, et al.
Publicado: (2019)

Phosphorylation of Mycobacterium tuberculosis Ser/Thr Phosphatase by PknA and PknB
por: Sajid, Andaleeb, et al.
Publicado: (2011)

Protein tyrosine phosphatases in glioma biology
por: Navis, Anna C., et al.
Publicado: (2009)

Metabolic regulation by protein tyrosine phosphatases
por: Knobler, Hilla, et al.
Publicado: (2014)

Role of Protein Tyrosine Phosphatases in Plants
por: Shankar, Alka, et al.
Publicado: (2015)

Crystal structure of the Yersinia tyrosine phosphatase
por: Bliska, James B.
Publicado: (1995)

Cannot write session to /tmp/vufind_sessions/sess_rjgavgfanss7r1cnko1cjph5sg