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Outside-in induction of the IFITM3 trafficking system by infections, including SARS-CoV-2, in the pathobiology of Alzheimer’s disease

BACKGROUND: IFITM3 is a viral restriction protein that enables sequestration of viral particles and subsequent trafficking to lysosomes. Recently, IFITM3 upregulation was found to induce gamma – secretase activity and the production of amyloid beta. The purpose of this study was to determine whether...

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Detalles Bibliográficos
Autores principales:	Vavougios, George D., Nday, Christiane, Pelidou, Sygliti-Henrietta, Gourgoulianis, Konstantinos I., Stamoulis, George, Doskas, Triantafyllos, Zarogiannis, Sotirios G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997139/ https://www.ncbi.nlm.nih.gov/pubmed/33817671 http://dx.doi.org/10.1016/j.bbih.2021.100243

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