Cargando…
Targeting the Activin Receptor Signaling to Counteract the Multi-Systemic Complications of Cancer and Its Treatments
Muscle wasting, i.e., cachexia, frequently occurs in cancer and associates with poor prognosis and increased morbidity and mortality. Anticancer treatments have also been shown to contribute to sustainment or exacerbation of cachexia, thus affecting quality of life and overall survival in cancer pat...
Autores principales: | Hulmi, Juha J., Nissinen, Tuuli A., Penna, Fabio, Bonetto, Andrea |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997313/ https://www.ncbi.nlm.nih.gov/pubmed/33671024 http://dx.doi.org/10.3390/cells10030516 |
Ejemplares similares
-
Activin Receptor Ligand Blocking and Cancer Have Distinct Effects on Protein and Redox Homeostasis in Skeletal Muscle and Liver
por: Hentilä, Jaakko, et al.
Publicado: (2019) -
Blocking Activin Receptor Ligands Is Not Sufficient to Rescue Cancer-Associated Gut Microbiota—A Role for Gut Microbial Flagellin in Colorectal Cancer and Cachexia?
por: Pekkala, Satu, et al.
Publicado: (2019) -
Treating cachexia using soluble ACVR2B improves survival, alters mTOR localization, and attenuates liver and spleen responses
por: Nissinen, Tuuli A., et al.
Publicado: (2018) -
Muscle NAD(+) depletion and Serpina3n as molecular determinants of murine cancer cachexia—the effects of blocking myostatin and activins
por: Hulmi, J.J., et al.
Publicado: (2020) -
NAD(+) repletion with niacin counteracts cancer cachexia
por: Beltrà, Marc, et al.
Publicado: (2023)