Endothelial Iron Homeostasis Regulates Blood-Brain Barrier Integrity via the HIF2α—Ve-Cadherin Pathway

The objective of this study was to investigate the molecular response to damage at the blood-brain barrier (BBB) and to elucidate critical pathways that might lead to effective treatment in central nervous system (CNS) pathologies in which the BBB is compromised. We have used a human, stem-cell deri...

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Detalles Bibliográficos
Autores principales: Rand, Daniel, Ravid, Orly, Atrakchi, Dana, Israelov, Hila, Bresler, Yael, Shemesh, Chen, Omesi, Liora, Liraz-Zaltsman, Sigal, Gosselet, Fabien, Maskrey, Taber S., Schnaider Beeri, Michal, Wipf, Peter, Cooper, Itzik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997362/
https://www.ncbi.nlm.nih.gov/pubmed/33670876
http://dx.doi.org/10.3390/pharmaceutics13030311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997362/
https://www.ncbi.nlm.nih.gov/pubmed/33670876
http://dx.doi.org/10.3390/pharmaceutics13030311

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