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Mechanistic Model for the Hsp90-Driven Opening of Human Argonaute
[Image: see text] The assembly of RNA-induced silencing complex (RISC) is a key process in small RNA-mediated gene silencing. Loading of small RNAs into Argonaute (Ago), the key player protein in the process, has been shown to depend on the Hsp90 chaperone machinery. Experimental single-molecule dat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997374/ https://www.ncbi.nlm.nih.gov/pubmed/32096993 http://dx.doi.org/10.1021/acs.jcim.0c00053 |