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Pt(II) versus Pt(IV) in Carbene Glycoconjugate Antitumor Agents: Minimal Structural Variations and Great Performance Changes
[Image: see text] Octahedral Pt(IV) complexes (2Pt–R) containing a glycoconjugate carbene ligand were prepared and fully characterized. These complexes are structural analogues to the trigonal bipyramidal Pt(II) species (1Pt–R) recently described. Thus, an unprecedented direct comparison between the...
Autores principales: | Annunziata, Alfonso, Amoresano, Angela, Cucciolito, Maria Elena, Esposito, Roberto, Ferraro, Giarita, Iacobucci, Ilaria, Imbimbo, Paola, Lucignano, Rosanna, Melchiorre, Massimo, Monti, Maria, Scognamiglio, Chiara, Tuzi, Angela, Monti, Daria Maria, Merlino, Antonello, Ruffo, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997382/ https://www.ncbi.nlm.nih.gov/pubmed/32129608 http://dx.doi.org/10.1021/acs.inorgchem.9b03683 |
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