Targeted design of drug binding sites in the main protease of SARS-CoV-2 reveals potential signatures of adaptation

Several existing drugs are currently being tested worldwide to treat COVID-19 patients. Recent data indicate that SARS-CoV-2 is rapidly evolving into more transmissible variants. It is therefore highly possible that SARS-CoV-2 can accumulate adaptive mutations modulating drug susceptibility and hamp...

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Detalles Bibliográficos
Autores principales: Padhi, Aditya K., Tripathi, Timir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997393/
https://www.ncbi.nlm.nih.gov/pubmed/33813274
http://dx.doi.org/10.1016/j.bbrc.2021.03.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997393/
https://www.ncbi.nlm.nih.gov/pubmed/33813274
http://dx.doi.org/10.1016/j.bbrc.2021.03.118

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