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IFNAR1 signaling in NK cells promotes persistent virus infection

Inhibition of type 1 interferon (IFN-I) signaling promotes the control of persistent virus infection, but the underlying mechanisms remain poorly understood. Here, we report that genetic ablation of Ifnar1 specifically in natural killer (NK) cells led to elevated numbers of T follicular helper cells...

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Detalles Bibliográficos
Autores principales: Huang, Zhe, Kang, Seung Goo, Li, Yunqiao, Zak, Jaroslav, Shaabani, Namir, Deng, Kaiyuan, Shepherd, Jovan, Bhargava, Raag, Teijaro, John R., Xiao, Changchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997497/
https://www.ncbi.nlm.nih.gov/pubmed/33771858
http://dx.doi.org/10.1126/sciadv.abb8087