Exploiting the acquired vulnerability of cisplatin-resistant tumors with a hypoxia-amplifying DNA repair–inhibiting (HYDRI) nanomedicine

Various cancers treated with cisplatin almost invariably develop drug resistance that is frequently caused by substantial DNA repair. We searched for acquired vulnerabilities of cisplatin-resistant cancers to identify undiscovered therapy. We herein found that cisplatin resistance of cancer cells co...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Wang, Xue, Yuan, Yuan, Chen, Haoting, Zhang, Lingpu, Xiao, Haihua, Chen, Jingqi, Zhao, Yongxiang, Chang, Jin, Guo, Weisheng, Liang, Xing-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997498/
https://www.ncbi.nlm.nih.gov/pubmed/33771859
http://dx.doi.org/10.1126/sciadv.abc5267

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