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Smart testing and selective quarantine for the control of epidemics()

This paper is based on the observation that, during Covid-19 epidemic, the choice of which individuals should be tested has an important impact on the effectiveness of selective confinement measures. This decision problem is closely related to the problem of optimal sensor selection, which is a very...

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Autores principales: Pezzutto, Matthias, Bono Rosselló, Nicolás, Schenato, Luca, Garone, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997562/
https://www.ncbi.nlm.nih.gov/pubmed/33814962
http://dx.doi.org/10.1016/j.arcontrol.2021.03.001
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author Pezzutto, Matthias
Bono Rosselló, Nicolás
Schenato, Luca
Garone, Emanuele
author_facet Pezzutto, Matthias
Bono Rosselló, Nicolás
Schenato, Luca
Garone, Emanuele
author_sort Pezzutto, Matthias
collection PubMed
description This paper is based on the observation that, during Covid-19 epidemic, the choice of which individuals should be tested has an important impact on the effectiveness of selective confinement measures. This decision problem is closely related to the problem of optimal sensor selection, which is a very active research subject in control engineering. The goal of this paper is to propose a policy to smartly select the individuals to be tested. The main idea is to model the epidemics as a stochastic dynamic system and to select the individual to be tested accordingly to some optimality criteria, e.g. to minimize the probability of undetected asymptomatic cases. Every day, the probability of infection of the different individuals is updated making use of the stochastic model of the phenomenon and of the information collected in the previous days. Simulations for a closed community of 10’000 individuals show that the proposed technique, coupled with a selective confinement policy, can reduce the spread of the disease while limiting the number of individuals confined if compared to the simple contact tracing of positive and to an off-line test selection strategy based on the number of contacts.
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spelling pubmed-79975622021-03-29 Smart testing and selective quarantine for the control of epidemics() Pezzutto, Matthias Bono Rosselló, Nicolás Schenato, Luca Garone, Emanuele Annu Rev Control Article This paper is based on the observation that, during Covid-19 epidemic, the choice of which individuals should be tested has an important impact on the effectiveness of selective confinement measures. This decision problem is closely related to the problem of optimal sensor selection, which is a very active research subject in control engineering. The goal of this paper is to propose a policy to smartly select the individuals to be tested. The main idea is to model the epidemics as a stochastic dynamic system and to select the individual to be tested accordingly to some optimality criteria, e.g. to minimize the probability of undetected asymptomatic cases. Every day, the probability of infection of the different individuals is updated making use of the stochastic model of the phenomenon and of the information collected in the previous days. Simulations for a closed community of 10’000 individuals show that the proposed technique, coupled with a selective confinement policy, can reduce the spread of the disease while limiting the number of individuals confined if compared to the simple contact tracing of positive and to an off-line test selection strategy based on the number of contacts. Elsevier Ltd. 2021 2021-03-26 /pmc/articles/PMC7997562/ /pubmed/33814962 http://dx.doi.org/10.1016/j.arcontrol.2021.03.001 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Pezzutto, Matthias
Bono Rosselló, Nicolás
Schenato, Luca
Garone, Emanuele
Smart testing and selective quarantine for the control of epidemics()
title Smart testing and selective quarantine for the control of epidemics()
title_full Smart testing and selective quarantine for the control of epidemics()
title_fullStr Smart testing and selective quarantine for the control of epidemics()
title_full_unstemmed Smart testing and selective quarantine for the control of epidemics()
title_short Smart testing and selective quarantine for the control of epidemics()
title_sort smart testing and selective quarantine for the control of epidemics()
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997562/
https://www.ncbi.nlm.nih.gov/pubmed/33814962
http://dx.doi.org/10.1016/j.arcontrol.2021.03.001
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