Cargando…
Designing Chimeric Molecules for Drug Discovery by Leveraging Chemical Biology
[Image: see text] After the first seed concept introduced in the 18th century, different disciplines have attributed different names to dual-functional molecules depending on their application, including bioconjugates, bifunctional compounds, multitargeting molecules, chimeras, hybrids, engineered c...
Autores principales: | Borsari, Chiara, Trader, Darci J., Tait, Annalisa, Costi, Maria P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997565/ https://www.ncbi.nlm.nih.gov/pubmed/32023055 http://dx.doi.org/10.1021/acs.jmedchem.9b01456 |
Ejemplares similares
-
Methods to Discover and Evaluate Proteasome Small Molecule Stimulators
por: Coleman, Rachel A., et al.
Publicado: (2019) -
Protein degradation profile reveals dynamic nature of 20S proteasome small molecule stimulation
por: Coleman, Rachel A., et al.
Publicado: (2021) -
Leveraging Microbial Genomes and Genomic Context for
Chemical Discovery
por: Kountz, Duncan J., et al.
Publicado: (2021) -
Epigenetic assays for chemical biology and drug discovery
por: Gul, Sheraz
Publicado: (2017) -
Leveraging molecular structure and bioactivity with chemical language models for de novo drug design
por: Moret, Michael, et al.
Publicado: (2023)