Insights into Cisplatin Binding to Uracil and Thiouracils from IRMPD Spectroscopy and Tandem Mass Spectrometry

[Image: see text] The monofunctional primary complexes cis-[PtCl(NH(3))(2)(L)](+), formed by the reaction of cisplatin, a major chemotherapeutic agent, with four nucleobases L, i.e., uracil (U), 2-thiouracil (2SU), 4-thiouracil (4SU), and 2,4-dithiouracil (24dSU), have been studied by a combination...

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Detalles Bibliográficos
Autores principales: Corinti, Davide, Crestoni, Maria Elisa, Chiavarino, Barbara, Fornarini, Simonetta, Scuderi, Debora, Salpin, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997577/
https://www.ncbi.nlm.nih.gov/pubmed/32233383
http://dx.doi.org/10.1021/jasms.0c00006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997577/
https://www.ncbi.nlm.nih.gov/pubmed/32233383
http://dx.doi.org/10.1021/jasms.0c00006

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