Splice-Switching Antisense Oligonucleotides as a Targeted Intrinsic Engineering Tool for Generating Armored Redirected T Cells

Modification of specificity of T cells for the use in adoptive transfer (CAR- or TCR-redirected T cells) has revolutionized the therapy of liquid tumors and some infectious diseases. However, several obstacles are still hampering the efficacy of such potent therapy, hence concurrent modification of...

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Detalles Bibliográficos
Autores principales: Ceccarello, Erica, Tabaglio, Tommaso, Koh, Sarene, Oei, Vincent, Teo, Winnie, Jonathan, Owen Julianto, Pavesi, Andrea, Chen, Qingfeng, Bertoletti, Antonio, Wee, Keng Boon, Guccione, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997720/
https://www.ncbi.nlm.nih.gov/pubmed/33567222
http://dx.doi.org/10.1089/nat.2020.0905

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