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Rapid response to the alpha-1 adrenergic agent phenylephrine in the perioperative period is impacted by genomics and ancestry
The emergence of genomic data in biobanks and health systems offers new ways to derive medically important phenotypes, including acute phenotypes occurring during inpatient clinical care. Here we study the genetic underpinnings of the rapid response to phenylephrine, an α1-adrenergic receptor agonis...
Autores principales: | Wenric, Stephane, Jeff, Janina M., Joseph, Thomas, Yee, Muh-Ching, Belbin, Gillian M., Owusu Obeng, Aniwaa, Ellis, Stephen B., Bottinger, Erwin P., Gottesman, Omri, Levin, Matthew A., Kenny, Eimear E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997806/ https://www.ncbi.nlm.nih.gov/pubmed/33168928 http://dx.doi.org/10.1038/s41397-020-00194-5 |
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