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A spatio-temporal model based on discrete latent variables for the analysis of COVID-19 incidence

We propose a model based on discrete latent variables, which are spatially associated and time specific, for the analysis of incident cases of SARS-CoV-2 infections. We assume that for each area the sequence of latent variables across time follows a Markov chain with initial and transition probabili...

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Detalles Bibliográficos
Autores principales: Bartolucci, Francesco, Farcomeni, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997863/
https://www.ncbi.nlm.nih.gov/pubmed/33816095
http://dx.doi.org/10.1016/j.spasta.2021.100504
Descripción
Sumario:We propose a model based on discrete latent variables, which are spatially associated and time specific, for the analysis of incident cases of SARS-CoV-2 infections. We assume that for each area the sequence of latent variables across time follows a Markov chain with initial and transition probabilities that also depend on latent variables in neighboring areas. The model is estimated by a Markov chain Monte Carlo algorithm based on a data augmentation scheme, in which the latent states are drawn together with the model parameters for each area and time. As an illustration we analyze incident cases of SARS-CoV-2 collected in Italy at regional level for the period from February 24, 2020, to January 17, 2021, corresponding to 48 weeks, where we use number of swabs as an offset. Our model identifies a common trend and, for every week, assigns each region to one among five distinct risk groups.