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A spatio-temporal model based on discrete latent variables for the analysis of COVID-19 incidence
We propose a model based on discrete latent variables, which are spatially associated and time specific, for the analysis of incident cases of SARS-CoV-2 infections. We assume that for each area the sequence of latent variables across time follows a Markov chain with initial and transition probabili...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997863/ https://www.ncbi.nlm.nih.gov/pubmed/33816095 http://dx.doi.org/10.1016/j.spasta.2021.100504 |
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author | Bartolucci, Francesco Farcomeni, Alessio |
author_facet | Bartolucci, Francesco Farcomeni, Alessio |
author_sort | Bartolucci, Francesco |
collection | PubMed |
description | We propose a model based on discrete latent variables, which are spatially associated and time specific, for the analysis of incident cases of SARS-CoV-2 infections. We assume that for each area the sequence of latent variables across time follows a Markov chain with initial and transition probabilities that also depend on latent variables in neighboring areas. The model is estimated by a Markov chain Monte Carlo algorithm based on a data augmentation scheme, in which the latent states are drawn together with the model parameters for each area and time. As an illustration we analyze incident cases of SARS-CoV-2 collected in Italy at regional level for the period from February 24, 2020, to January 17, 2021, corresponding to 48 weeks, where we use number of swabs as an offset. Our model identifies a common trend and, for every week, assigns each region to one among five distinct risk groups. |
format | Online Article Text |
id | pubmed-7997863 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-79978632021-03-29 A spatio-temporal model based on discrete latent variables for the analysis of COVID-19 incidence Bartolucci, Francesco Farcomeni, Alessio Spat Stat Article We propose a model based on discrete latent variables, which are spatially associated and time specific, for the analysis of incident cases of SARS-CoV-2 infections. We assume that for each area the sequence of latent variables across time follows a Markov chain with initial and transition probabilities that also depend on latent variables in neighboring areas. The model is estimated by a Markov chain Monte Carlo algorithm based on a data augmentation scheme, in which the latent states are drawn together with the model parameters for each area and time. As an illustration we analyze incident cases of SARS-CoV-2 collected in Italy at regional level for the period from February 24, 2020, to January 17, 2021, corresponding to 48 weeks, where we use number of swabs as an offset. Our model identifies a common trend and, for every week, assigns each region to one among five distinct risk groups. Elsevier B.V. 2022-06 2021-03-27 /pmc/articles/PMC7997863/ /pubmed/33816095 http://dx.doi.org/10.1016/j.spasta.2021.100504 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Bartolucci, Francesco Farcomeni, Alessio A spatio-temporal model based on discrete latent variables for the analysis of COVID-19 incidence |
title | A spatio-temporal model based on discrete latent variables for the analysis of COVID-19 incidence |
title_full | A spatio-temporal model based on discrete latent variables for the analysis of COVID-19 incidence |
title_fullStr | A spatio-temporal model based on discrete latent variables for the analysis of COVID-19 incidence |
title_full_unstemmed | A spatio-temporal model based on discrete latent variables for the analysis of COVID-19 incidence |
title_short | A spatio-temporal model based on discrete latent variables for the analysis of COVID-19 incidence |
title_sort | spatio-temporal model based on discrete latent variables for the analysis of covid-19 incidence |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997863/ https://www.ncbi.nlm.nih.gov/pubmed/33816095 http://dx.doi.org/10.1016/j.spasta.2021.100504 |
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