Cargando…
Characterizing advanced breast cancer heterogeneity and treatment resistance through serial biopsies and comprehensive analytics
Molecular heterogeneity in metastatic breast cancer presents multiple clinical challenges in accurately characterizing and treating the disease. Current diagnostic approaches offer limited ability to assess heterogeneity that exists among multiple metastatic lesions throughout the treatment course....
Autores principales: | Li, Allen, Keck, Jamie M., Parmar, Swapnil, Patterson, Janice, Labrie, Marilyne, Creason, Allison L., Johnson, Brett E., Downey, Molly, Thomas, George, Beadling, Carol, Heiser, Laura M., Kolodzie, Annette, Guimaraes, Alexander R., Corless, Christopher L., Gray, Joe W., Mills, Gordon B., Bergan, Raymond C., Mitri, Zahi I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997873/ https://www.ncbi.nlm.nih.gov/pubmed/33772089 http://dx.doi.org/10.1038/s41698-021-00165-4 |
Ejemplares similares
-
Multiomics analysis of serial PARP inhibitor treated metastatic TNBC inform on rational combination therapies
por: Labrie, Marilyne, et al.
Publicado: (2021) -
An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer
por: Johnson, Brett E., et al.
Publicado: (2022) -
Implementing a comprehensive translational oncology platform: from molecular testing to actionability
por: Mitri, Zahi I., et al.
Publicado: (2018) -
A multi-encoder variational autoencoder controls multiple transformational features in single-cell image analysis
por: Ternes, Luke, et al.
Publicado: (2022) -
Gene expression of the IGF pathway family distinguishes subsets of gastrointestinal stromal tumors wild type for KIT and PDGFRA
por: Beadling, Carol, et al.
Publicado: (2013)