Quantification of T cell clonality in human T cell leukaemia virus type-1 carriers can detect the development of adult T cell leukaemia early

Adult T cell leukaemia/lymphoma (ATL) arises from clonally expanded T cells that are infected with human T cell leukaemia virus type-1 (HTLV-1). Here, we show that ATL can be detected early in HTLV-1-carriers through quantification of T-cell receptor (TCR)Vβ subunit diversity on T-cells infected wit...

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Detalles Bibliográficos
Autores principales: Wolf, Sonia N., Haddow, Jana, Greiller, Claire, Taylor, Graham P., Cook, Lucy B. M., Rowan, Aileen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997885/
https://www.ncbi.nlm.nih.gov/pubmed/33771974
http://dx.doi.org/10.1038/s41408-021-00458-8

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