E3 ubiquitin ligase Grail promotes hepatic steatosis through Sirt1 inhibition

In obese adults, nonalcoholic fatty liver disease (NAFLD) is accompanied by multiple metabolic dysfunctions. Although upregulated hepatic fatty acid synthesis has been identified as a crucial mediator of NAFLD development, the underlying mechanisms are yet to be elucidated. In this study, we reporte...

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Detalles Bibliográficos
Autores principales: Liu, Pei-Yao, Chen, Cheng-Cheung, Chin, Chia-Ying, Liu, Te-Jung, Tsai, Wen-Chiuan, Chou, Jian-Liang, Huang, Chuan-Yu, Chen, Yu-Guang, Chen, Ying-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997893/
https://www.ncbi.nlm.nih.gov/pubmed/33771967
http://dx.doi.org/10.1038/s41419-021-03608-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997893/
https://www.ncbi.nlm.nih.gov/pubmed/33771967
http://dx.doi.org/10.1038/s41419-021-03608-9

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