Host-derived lipids orchestrate pulmonary γδ T cell response to provide early protection against influenza virus infection

Innate immunity is important for host defense by eliciting rapid anti-viral responses and bridging adaptive immunity. Here, we show that endogenous lipids released from virus-infected host cells activate lung γδ T cells to produce interleukin 17 A (IL-17A) for early protection against H1N1 influenza...

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Detalles Bibliográficos
Autores principales: Wang, Xiaohui, Lin, Xiang, Zheng, Zihan, Lu, Bingtai, Wang, Jun, Tan, Andy Hee-Meng, Zhao, Meng, Loh, Jia Tong, Ng, Sze Wai, Chen, Qian, Xiao, Fan, Huang, Enyu, Ko, King-Hung, Huang, Zhong, Li, Jingyi, Kok, Kin-Hang, Lu, Gen, Liu, Xiaohui, Lam, Kong-Peng, Liu, Wanli, Zhang, Yuxia, Yuen, Kwok-Yung, Mak, Tak Wah, Lu, Liwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997921/
https://www.ncbi.nlm.nih.gov/pubmed/33772013
http://dx.doi.org/10.1038/s41467-021-22242-9

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