Cargando…

Co-dependency for MET and FGFR1 in basal triple-negative breast cancers

Triple-negative breast cancer (TNBC) is a heterogeneous disease that lacks both effective patient stratification strategies and therapeutic targets. Whilst elevated levels of the MET receptor tyrosine kinase are associated with TNBCs and predict poor clinical outcome, the functional role of MET in T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sung, Vanessa Y. C., Knight, Jennifer F., Johnson, Radia M., Stern, Yaakov E., Saleh, Sadiq M., Savage, Paul, Monast, Anie, Zuo, Dongmei, Duhamel, Stéphanie, Park, Morag
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997957/ https://www.ncbi.nlm.nih.gov/pubmed/33772015 http://dx.doi.org/10.1038/s41523-021-00238-4

Ejemplares similares

Met–HER3 crosstalk supports proliferation via MPZL3 in MET-amplified cancer cells
por: Stern, Yaakov E., et al.
Publicado: (2022)

KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer
por: Knight, Jennifer F., et al.
Publicado: (2018)

FGFR3 signaling and function in triple negative breast cancer
por: Chew, Nicole J., et al.
Publicado: (2020)

Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers
por: Linklater, Erik S., et al.
Publicado: (2016)

Are Basal-Like and Non-Basal-Like Triple-Negative Breast Cancers Really Different?
por: Dogra, Atika, et al.
Publicado: (2020)

Crk adaptor proteins act as key signaling integrators for breast tumorigenesis
por: Fathers, Kelly E, et al.
Publicado: (2012)

Are triple-negative tumours and basal-like breast cancer synonymous?
por: Rakha, Emad A, et al.
Publicado: (2007)

DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior
por: Ioannou, Maria S., et al.
Publicado: (2015)

Importance of Copy Number Alterations of FGFR1 and C-MYC Genes in Triple Negative Breast Cancer
por: Nedeljković, Milica, et al.
Publicado: (2019)

FGFR blockade boosts T cell infiltration into triple-negative breast cancer by regulating cancer-associated fibroblasts
por: Wu, Yushen, et al.
Publicado: (2022)

Overexpression of FGFR2 contributes to inherent resistance to MET inhibitors in MET-amplified patient-derived gastric cancer xenografts
por: LIU, KAI, et al.
Publicado: (2015)

The Epigenetics of Triple-Negative and Basal-Like Breast Cancer: Current Knowledge
por: Temian, Daiana Cosmina, et al.
Publicado: (2018)

High MET expression is an adverse prognostic factor in patients with triple-negative breast cancer
por: Zagouri, F, et al.
Publicado: (2013)

cMET Activation and EGFR-Directed Therapy Resistance in Triple-Negative Breast Cancer
por: Sohn, Joohyuk, et al.
Publicado: (2014)

Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple‐Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy
por: Lei, Josh Haipeng, et al.
Publicado: (2021)

ROR1 Potentiates FGFR Signaling in Basal-Like Breast Cancer
por: Pandey, Gaurav, et al.
Publicado: (2019)

Triple-negative, basal-like, and quintuple-negative breast cancers: better prediction model for survival
por: Choi, Yoon-La, et al.
Publicado: (2010)

MET-Pyk2 Axis Mediates Acquired Resistance to FGFR Inhibition in Cancer Cells
por: Kitowska, Kamila, et al.
Publicado: (2021)

FGFR blockade inhibits targeted therapy-tolerant persister in basal FGFR1- and FGF2-high cancers with driver oncogenes
por: Furugaki, Koh, et al.
Publicado: (2023)

Are triple-negative tumours and basal-like breast cancer synonymous? Authors' response
por: Kreike, Bas, et al.
Publicado: (2007)

Maspin expression is frequent and correlates with basal markers in triple-negative breast cancer
por: Umekita, Yoshihisa, et al.
Publicado: (2011)

p16 expression correlates with basal-like triple-negative breast carcinoma
por: Abou-Bakr, Amany A, et al.
Publicado: (2013)

Brassinin Promotes the Degradation of Tie2 and FGFR1 in Endothelial Cells and Inhibits Triple-Negative Breast Cancer Angiogenesis
por: Gu, Yuan, et al.
Publicado: (2022)

Comment on ‘High MET expression is an adverse prognostic factor in patients with triple-negative breast cancer'
por: Ho-Yen, C, et al.
Publicado: (2013)

Dasatinib Treatment Increases Sensitivity to c-Met Inhibition in Triple-Negative Breast Cancer Cells
por: Gaule, Patricia, et al.
Publicado: (2019)

Met receptor tyrosine kinase signals through a cortactin–Gab1 scaffold complex, to mediate invadopodia
por: Rajadurai, Charles V., et al.
Publicado: (2012)

Correction: triple-negative, basal-like, and quintuple-negative breast cancers: better prediction model for survival
por: Choi, Yoon-La, et al.
Publicado: (2011)

FGFR2 is required for airway basal cell self-renewal and terminal differentiation
por: Balasooriya, Gayan I., et al.
Publicado: (2017)

Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility
por: Li, Ran, et al.
Publicado: (2015)

Evaluation of MET T1010I and MET rs40239 single-nucleotide polymorphisms in triple-negative breast cancer: a case–control study
por: Kalapanida, Despoina, et al.
Publicado: (2019)

Predicting Relapse in Patients With Triple Negative Breast Cancer (TNBC) Using a Deep-Learning Approach
por: Yu, Guangyuan, et al.
Publicado: (2020)

Gene amplification of EGFR, HER2, FGFR2 and MET in esophageal squamous cell carcinoma
por: KATO, HIROAKI, et al.
Publicado: (2013)

Activation of the Met kinase confers acquired drug resistance in FGFR-targeted lung cancer therapy
por: Kim, S-M, et al.
Publicado: (2016)

An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium
por: Balasooriya, Gayan I., et al.
Publicado: (2016)

Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas
por: Kreike, Bas, et al.
Publicado: (2007)

A clinically relevant gene signature in triple negative and basal-like breast cancer
por: Rody, Achim, et al.
Publicado: (2011)

Calpain system protein expression in basal-like and triple-negative invasive breast cancer
por: Storr, S. J., et al.
Publicado: (2012)

Modulatory Role of microRNAs in Triple Negative Breast Cancer with Basal-Like Phenotype
por: Angius, Andrea, et al.
Publicado: (2020)

Hypoxia Triggers TAZ Phosphorylation in Basal A Triple Negative Breast Cancer Cells
por: Liu, Qiuyu, et al.
Publicado: (2022)

Differential responses to kinase inhibition in FGFR2-addicted triple negative breast cancer cells: a quantitative phosphoproteomics study
por: Cunningham, Debbie L., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vd47fkhbhhe9o0qq4ilhg5og9o