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Analysis of the effects of spaceflight and local administration of thrombopoietin to a femoral defect injury on distal skeletal sites
With increased human presence in space, bone loss and fractures will occur. Thrombopoietin (TPO) is a recently patented bone healing agent. Here, we investigated the systemic effects of TPO on mice subjected to spaceflight and sustaining a bone fracture. Forty, 9-week-old, male, C57BL/6 J were divid...
Autores principales: | Zamarioli, Ariane, Campbell, Zachery R., Maupin, Kevin A., Childress, Paul J., Ximenez, Joao P. B., Adam, Gremah, Chakraborty, Nabarun, Gautam, Aarti, Hammamieh, Rasha, Kacena, Melissa A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7997973/ https://www.ncbi.nlm.nih.gov/pubmed/33772025 http://dx.doi.org/10.1038/s41526-021-00140-0 |
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