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RETRACTED ARTICLE: Noninvasive thrombectomy of graft by nano-magnetic ablating particles
Artificial vascular treatment is an emerging interdisciplinary subject of medicine. Although the use of artificial vessels has led to many successful advancements, blood clotting remains a major challenge, especially in terms of mural clots created along the vessel wall that do not completely block...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998024/ https://www.ncbi.nlm.nih.gov/pubmed/33772062 http://dx.doi.org/10.1038/s41598-021-86291-2 |
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author | Moghanizadeh, Abbas Ashrafizadeh, Fakhreddin Varshosaz, Jaleh Kharaziha, Mahshid Ferreira, Antoine |
author_facet | Moghanizadeh, Abbas Ashrafizadeh, Fakhreddin Varshosaz, Jaleh Kharaziha, Mahshid Ferreira, Antoine |
author_sort | Moghanizadeh, Abbas |
collection | PubMed |
description | Artificial vascular treatment is an emerging interdisciplinary subject of medicine. Although the use of artificial vessels has led to many successful advancements, blood clotting remains a major challenge, especially in terms of mural clots created along the vessel wall that do not completely block the vessel. The main objective of this study is to present a method for declotting artificial vessels. This research introduces a novel thrombectomy technique in artificial vessels by employing nano-magnetic particles under a rotating magnetic field to remove mural clots in artificial vessels. A mathematical model describes the relationship between process parameters. In vitro tests confirm the feasibility of nano-magnetic thrombectomy in cleaning and declotting artificial vessels. The results show that the clot fragments are nano-sized, which eliminates the risk of distal emboli as a concern of using current atherectomy techniques. Meanwhile, no damage to the artificial vessels is observed. The results show that the frequency of rotating the magnetic field has the greatest effect on clot removal. The conceptual principles stated in this study also have the potential to be used in other vascular depositions, such as the accumulation of lipids, and calcification atherosclerosis. |
format | Online Article Text |
id | pubmed-7998024 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-79980242021-03-30 RETRACTED ARTICLE: Noninvasive thrombectomy of graft by nano-magnetic ablating particles Moghanizadeh, Abbas Ashrafizadeh, Fakhreddin Varshosaz, Jaleh Kharaziha, Mahshid Ferreira, Antoine Sci Rep Article Artificial vascular treatment is an emerging interdisciplinary subject of medicine. Although the use of artificial vessels has led to many successful advancements, blood clotting remains a major challenge, especially in terms of mural clots created along the vessel wall that do not completely block the vessel. The main objective of this study is to present a method for declotting artificial vessels. This research introduces a novel thrombectomy technique in artificial vessels by employing nano-magnetic particles under a rotating magnetic field to remove mural clots in artificial vessels. A mathematical model describes the relationship between process parameters. In vitro tests confirm the feasibility of nano-magnetic thrombectomy in cleaning and declotting artificial vessels. The results show that the clot fragments are nano-sized, which eliminates the risk of distal emboli as a concern of using current atherectomy techniques. Meanwhile, no damage to the artificial vessels is observed. The results show that the frequency of rotating the magnetic field has the greatest effect on clot removal. The conceptual principles stated in this study also have the potential to be used in other vascular depositions, such as the accumulation of lipids, and calcification atherosclerosis. Nature Publishing Group UK 2021-03-26 /pmc/articles/PMC7998024/ /pubmed/33772062 http://dx.doi.org/10.1038/s41598-021-86291-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Moghanizadeh, Abbas Ashrafizadeh, Fakhreddin Varshosaz, Jaleh Kharaziha, Mahshid Ferreira, Antoine RETRACTED ARTICLE: Noninvasive thrombectomy of graft by nano-magnetic ablating particles |
title | RETRACTED ARTICLE: Noninvasive thrombectomy of graft by nano-magnetic ablating particles |
title_full | RETRACTED ARTICLE: Noninvasive thrombectomy of graft by nano-magnetic ablating particles |
title_fullStr | RETRACTED ARTICLE: Noninvasive thrombectomy of graft by nano-magnetic ablating particles |
title_full_unstemmed | RETRACTED ARTICLE: Noninvasive thrombectomy of graft by nano-magnetic ablating particles |
title_short | RETRACTED ARTICLE: Noninvasive thrombectomy of graft by nano-magnetic ablating particles |
title_sort | retracted article: noninvasive thrombectomy of graft by nano-magnetic ablating particles |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998024/ https://www.ncbi.nlm.nih.gov/pubmed/33772062 http://dx.doi.org/10.1038/s41598-021-86291-2 |
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