Cargando…
Preclinical Investigation of Trifluoperazine as a Novel Therapeutic Agent for the Treatment of Pulmonary Arterial Hypertension
Trifluoperazine (TFP), an antipsychotic drug approved by the Food and Drug Administration, has been show to exhibit anti-cancer effects. Pulmonary arterial hypertension (PAH) is a devastating disease characterized by a progressive obliteration of small pulmonary arteries (PAs) due to exaggerated pro...
Autores principales: | Grobs, Yann, Awada, Charifa, Lemay, Sarah-Eve, Romanet, Charlotte, Bourgeois, Alice, Toro, Victoria, Nadeau, Valérie, Shimauchi, Kana, Orcholski, Mark, Breuils-Bonnet, Sandra, Tremblay, Eve, Provencher, Steeve, Paulin, Roxane, Boucherat, Olivier, Bonnet, Sébastien |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998101/ https://www.ncbi.nlm.nih.gov/pubmed/33805714 http://dx.doi.org/10.3390/ijms22062919 |
Ejemplares similares
-
PARP1-PKM2 Axis Mediates Right Ventricular Failure Associated With Pulmonary Arterial Hypertension
por: Shimauchi, Tsukasa, et al.
Publicado: (2022) -
Implication of EZH2 in the Pro-Proliferative and Apoptosis-Resistant Phenotype of Pulmonary Artery Smooth Muscle Cells in PAH: A Transcriptomic and Proteomic Approach
por: Habbout, Karima, et al.
Publicado: (2021) -
Fetal Gene Reactivation in Pulmonary Arterial Hypertension: GOOD, BAD, or BOTH?
por: Lemay, Sarah-Eve, et al.
Publicado: (2021) -
Dual ET(A)/ET(B) blockade with macitentan improves both vascular remodeling and angiogenesis in pulmonary arterial hypertension
por: Nadeau, Valerie, et al.
Publicado: (2017) -
Right Ventricular Dysfunction in Pulmonary Hypertension: Is Resistin a Promising Target?
por: Lemay, Sarah‐Eve, et al.
Publicado: (2023)