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Dexamethasone Induces the Expression and Function of Tryptophan-2-3-Dioxygenase in SK-MEL-28 Melanoma Cells

Tryptophan-2,3-dioxygenase (TDO) is one of the key tryptophan-catabolizing enzymes with immunoregulatory properties in cancer. Contrary to expectation, clinical trials showed that inhibitors of the ubiquitously expressed enzyme, indoleamine-2,3-dioxygenase-1 (IDO1), do not provide benefits in melano...

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Detalles Bibliográficos
Autores principales:	Cecchi, Marta, Paccosi, Sara, Silvano, Angela, Eid, Ali Hussein, Parenti, Astrid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998133/ https://www.ncbi.nlm.nih.gov/pubmed/33806305 http://dx.doi.org/10.3390/ph14030211

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