Synthesis of Two Methotrexate Prodrugs for Optimizing Drug Loading into Liposomes

Methotrexate (MTX), a compound originally used as an anticancer drug, has also found applications in a broad variety of autoimmune disorders thanks to its anti-inflammation and immunomodulatory functions. The broad application of MTX is anyway limited by its poor solubility in biological fluids, its...

Descripción completa

Detalles Bibliográficos
Autores principales: Di Francesco, Valentina, Di Francesco, Martina, Decuzzi, Paolo, Palomba, Roberto, Ferreira, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998143/
https://www.ncbi.nlm.nih.gov/pubmed/33806703
http://dx.doi.org/10.3390/pharmaceutics13030332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998143/
https://www.ncbi.nlm.nih.gov/pubmed/33806703
http://dx.doi.org/10.3390/pharmaceutics13030332

Ejemplares similares