A Novel ALDH2 Activator AD-9308 Improves Diastolic and Systolic Myocardial Functions in Streptozotocin-Induced Diabetic Mice

Diabetes mellitus has reached epidemic proportion worldwide. One of the diabetic complications is cardiomyopathy, characterized by early left ventricular (LV) diastolic dysfunction, followed by development of systolic dysfunction and ventricular dilation at a late stage. The pathogenesis is multifac...

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Detalles Bibliográficos
Autores principales: Lee, Hsiao-Lin, Hee, Siow-Wey, Hsuan, Chin-Feng, Yang, Wenjin, Huang, Jing-Yong, Lin, Ya-Ling, Hsu, Chih-Neng, Hwang, Juey-Jen, Chen, Shiau-Mei, Ding, Zhi-Zhong, Lee, Tung-Yuan, Lin, Yu-Chiao, Tsai, Feng-Chiao, Su, Wei-Lun, Chueh, Li-Yun, Hsieh, Meng-Lun, Chen, Che-Hong, Mochly-Rosen, Daria, Chang, Yi-Cheng, Chuang, Lee-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998151/
https://www.ncbi.nlm.nih.gov/pubmed/33805825
http://dx.doi.org/10.3390/antiox10030450

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