Design and Comprehensive Characterization of Tetramethylpyrazine (TMP) for Targeted Lung Delivery as Inhalation Aerosols in Pulmonary Hypertension (PH): In Vitro Human Lung Cell Culture and In Vivo Efficacy

This is the first study reporting on the design and development innovative inhaled formulations of the novel natural product antioxidant therapeutic, tetramethylpyrazine (TMP), also known as ligustrazine. TMP is obtained from Chinese herbs belonging to the class of Ligusticum. It is known to have an...

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Detalles Bibliográficos
Autores principales: Muralidharan, Priya, Acosta, Maria F., Gomez, Alexan I., Grijalva, Carissa, Tang, Haiyang, Yuan, Jason X.-J., Mansour, Heidi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998162/
https://www.ncbi.nlm.nih.gov/pubmed/33799587
http://dx.doi.org/10.3390/antiox10030427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998162/
https://www.ncbi.nlm.nih.gov/pubmed/33799587
http://dx.doi.org/10.3390/antiox10030427

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