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Coupling Mass Spectral and Genomic Information to Improve Bacterial Natural Product Discovery Workflows

Bacterial natural products possess potent bioactivities and high structural diversity and are typically encoded in biosynthetic gene clusters. Traditional natural product discovery approaches rely on UV- and bioassay-guided fractionation and are limited in terms of dereplication. Recent advances in...

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Detalles Bibliográficos
Autor principal: Crüsemann, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998270/
https://www.ncbi.nlm.nih.gov/pubmed/33807702
http://dx.doi.org/10.3390/md19030142