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Coupling Mass Spectral and Genomic Information to Improve Bacterial Natural Product Discovery Workflows
Bacterial natural products possess potent bioactivities and high structural diversity and are typically encoded in biosynthetic gene clusters. Traditional natural product discovery approaches rely on UV- and bioassay-guided fractionation and are limited in terms of dereplication. Recent advances in...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998270/ https://www.ncbi.nlm.nih.gov/pubmed/33807702 http://dx.doi.org/10.3390/md19030142 |