Cargando…

α-Solanine Inhibits Proliferation, Invasion, and Migration, and Induces Apoptosis in Human Choriocarcinoma JEG-3 Cells In Vitro and In Vivo

α-Solanine, a bioactive compound mainly found in potato, exhibits anti-cancer activity towards multiple cancer cells. However, its effects on human choriocarcinoma have not been evaluated. In the present study, we investigated the effect of α-solanine on cell proliferation and apoptosis in human cho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Ting, Yuan, Wei, Li, Chen, Chen, Zhilong, Wen, Yuting, Zheng, Qiyi, Yang, Qing, Xiong, Xingyao, Yuan, Anwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998402/ https://www.ncbi.nlm.nih.gov/pubmed/33805658 http://dx.doi.org/10.3390/toxins13030210

Ejemplares similares

α-Solanine Causes Cellular Dysfunction of Human Trophoblast Cells via Apoptosis and Autophagy
por: Chen, Zhilong, et al.
Publicado: (2021)

Myeloperoxidase enhances the migration and invasion of human choriocarcinoma JEG-3 cells
por: Mihalic, Z.N., et al.
Publicado: (2023)

Reduction of pl-CSA through ChSy-2 knockout inhibits tumorigenesis and metastasis of choriocarcinoma in JEG3 cells
por: Zhang, Juzuo, et al.
Publicado: (2021)

StarD7 Knockdown Modulates ABCG2 Expression, Cell Migration, Proliferation, and Differentiation of Human Choriocarcinoma JEG-3 Cells
por: Flores-Martín, Jésica, et al.
Publicado: (2012)

Toxoplasma gondii dense granule protein 15 induces apoptosis in choriocarcinoma JEG-3 cells through endoplasmic reticulum stress
por: Wei, Wei, et al.
Publicado: (2018)

Antitumor Efficacy of α-Solanine against Pancreatic Cancer In Vitro and In Vivo
por: Lv, Chongqing, et al.
Publicado: (2014)

Solanine Attenuates Hepatocarcinoma Migration and Invasion Induced by Acetylcholine
por: Lin, Liang-Tzung, et al.
Publicado: (2020)

The role of PPARγ in TBBPA-mediated endocrine disrupting effects in human choriocarcinoma JEG-3 cells
por: Honkisz, Ewelina, et al.
Publicado: (2015)

Transthyretin regulates the migration and invasion of JEG-3 cells
por: Gong, Liyun, et al.
Publicado: (2017)

Corrigendum to Solanine Attenuated Hepatocarcinoma Migration and Invasion Induced by Acetylcholine
Publicado: (2022)

The comparison of pegylated liposomal doxorubicin and beta-carotene effects on JAR and JEG-3 choriocarcinoma human cell culture models
por: Erol, Seyit Ahmet, et al.
Publicado: (2020)

Intranuclear Crosstalk between Extracellular Regulated Kinase1/2 and Signal Transducer and Activator of Transcription 3 Regulates JEG-3 Choriocarcinoma Cell Invasion and Proliferation
por: Morales-Prieto, Diana M., et al.
Publicado: (2013)

JEG Gamma project
por: CERN. Geneva. Experimental Physics (EP) division
Publicado: (-)

Evaluation of antifungal and cytotoxic activity of trans-Chalcone and α-Solanine
por: Komoto, Tatiana Takahasi, et al.
Publicado: (2014)

Solanaceae glycoalkaloids: α-solanine and α-chaconine modify the cardioinhibitory activity of verapamil
por: Chowański, Szymon, et al.
Publicado: (2022)

Solanine Induces Mitochondria-Mediated Apoptosis in Human Pancreatic Cancer Cells
por: Sun, Hongwei, et al.
Publicado: (2014)

Contribution of Ezrin on the Cell Surface Plasma Membrane Localization of Programmed Cell Death Ligand-1 in Human Choriocarcinoma JEG-3 Cells
por: Tameishi, Mayuka, et al.
Publicado: (2021)

α-Solanine inhibits growth and metastatic potential of human colorectal cancer cells
por: Yan, Xia, et al.
Publicado: (2020)

HSPC117 Is Regulated by Epigenetic Modification and Is Involved in the Migration of JEG-3 Cells
por: Ma, Hong, et al.
Publicado: (2014)

Development of New Antibodies and an ELISA System to Detect the Potato Alkaloids α-Solanine and α-Chaconine
por: Okada, Kohki, et al.
Publicado: (2023)

A narrative review of the antitumor studies of solanine
por: Luo, Shan, et al.
Publicado: (2021)

Network pharmacology-based strategy to investigate the effect and mechanism of α-solanine against glioma
por: Wang, ChunPeng, et al.
Publicado: (2023)

Liquid Chromatography Mass Spectrometry Quantification of α-solanine, α-chaconine, and Solanidine in Potato Protein Isolates
por: Nielsen, Søren D., et al.
Publicado: (2020)

MyD88 and TRIF mediate the cyclic adenosine monophosphate (cAMP) induced corticotropin releasing hormone (CRH) expression in JEG3 choriocarcinoma cell line
por: Uh, Andy, et al.
Publicado: (2009)

Crosstalk between the p38 and TGF-β signaling pathways through TβRI, TβRII and Smad3 expression in plancental choriocarcinoma JEG-3 cells
por: TAN, YUSI, et al.
Publicado: (2014)

α-Chaconine and α-Solanine Inhibit RL95-2 Endometrium Cancer Cell Proliferation by Reducing Expression of Akt (Ser473) and ERα (Ser167)
por: Karaboğa Arslan, Ayşe Kübra, et al.
Publicado: (2018)

α-Solanine Inhibits Invasion of Human Prostate Cancer Cell by Suppressing Epithelial-Mesenchymal Transition and MMPs Expression
por: Shen, Kun-Hung, et al.
Publicado: (2014)

Potential of Alpha-(α)-Solanine as a Natural Inhibitor of Fungus Causing Leaf Spot Disease in Strawberry
por: Xu, Ning, et al.
Publicado: (2023)

Identification of Adrenomedullin-Induced S-Nitrosylated Proteins in JEG-3 Placental Cells
por: Li, Yingting, et al.
Publicado: (2021)

Effect and mechanism of the aβ2-GP I/rhβ2-GP I complex on JEG-3 cell proliferation, migration and invasion
por: Lu, Xiumin, et al.
Publicado: (2018)

Ugens debattør Jeg er blevet lunere på atomkraft
Publicado: (2008)

Cyclosporin A protects JEG-3 cells against oxidative stress-induced apoptosis by inhibiting the p53 and JNK/p38 signaling pathways
por: He, Bin, et al.
Publicado: (2020)

Application of a JEG-3 organoid model to study HLA-G function in the trophoblast
por: Zhuang, Bai-Mei, et al.
Publicado: (2023)

Forskolin Induces Endocrine Disturbance in Human JEG-3 Placental Cells
por: Rat, Patrice, et al.
Publicado: (2022)

The Combination of Lead and Bacillus coagulans R11 Increased the Concentration of Alpha-Solanine in the Cecum of Laying Hens and the Pathogens Abundance Decreased
por: Xing, Si-Cheng, et al.
Publicado: (2020)

A multifunctional enzyme portfolio for α-chaconine and α-solanine degradation in the Phthorimaea operculella gut bacterium Glutamicibacter halophytocola S2 encoded in a trisaccharide utilization locus
por: Wang, Wenqian, et al.
Publicado: (2022)

Lentivirus-mediated RNA interference targeting the H19 gene inhibits cell proliferation and apoptosis in human choriocarcinoma cell line JAR
por: Yu, Li-Li, et al.
Publicado: (2013)

α-Solanine induces ROS-mediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway
por: Hasanain, M, et al.
Publicado: (2015)

A Reliable and Reproducible Model for Assessing the Effect of Different Concentrations of α-Solanine on Rat Bone Marrow Mesenchymal Stem Cells
por: Ordóñez-Vásquez, Adriana, et al.
Publicado: (2017)

A challenging case of suspected solanine toxicity in an eleven-year-old Saudi boy
por: Al Masaoud, Fatimah S., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qoag78ahkjpi0ta7gdv7mdm923