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Novel PEGylated Lipid Nanoparticles Have a High Encapsulation Efficiency and Effectively Deliver MRTF-B siRNA in Conjunctival Fibroblasts

The master regulator of the fibrosis cascade is the myocardin-related transcription factor/serum response factor (MRTF/SRF) pathway, making it a key target for anti-fibrotic therapeutics. In the past, inhibitors and small interfering RNAs (siRNAs) targeting the MRTF-B gene have been deployed to coun...

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Detalles Bibliográficos
Autores principales:	Sanghani, Amisha, Kafetzis, Konstantinos N., Sato, Yusuke, Elboraie, Salsabil, Fajardo-Sanchez, Julia, Harashima, Hideyoshi, Tagalakis, Aristides D., Yu-Wai-Man, Cynthia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998417/ https://www.ncbi.nlm.nih.gov/pubmed/33805660 http://dx.doi.org/10.3390/pharmaceutics13030382

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