Cargando…

Physalis peruviana-Derived Physapruin A (PHA) Inhibits Breast Cancer Cell Proliferation and Induces Oxidative-Stress-Mediated Apoptosis and DNA Damage

Breast cancer expresses clinically heterogeneous characteristics and requires multipurpose drug development for curing the different tumor subtypes. Many withanolides have been isolated from Physalis species showing anticancer effects, but the anticancer function of physapruin A (PHA) has rarely bee...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Tzu-Jung, Cheng, Yuan-Bin, Lin, Li-Ching, Tsai, Yi-Hong, Yao, Bo-Yi, Tang, Jen-Yang, Chang, Fang-Rong, Yen, Chia-Hung, Ou-Yang, Fu, Chang, Hsueh-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998541/ https://www.ncbi.nlm.nih.gov/pubmed/33807834 http://dx.doi.org/10.3390/antiox10030393

Ejemplares similares

Physapruin A Enhances DNA Damage and Inhibits DNA Repair to Suppress Oral Cancer Cell Proliferation
por: Yu, Tzu-Jung, et al.
Publicado: (2022)

Physapruin A Exerts Endoplasmic Reticulum Stress to Trigger Breast Cancer Cell Apoptosis via Oxidative Stress
por: Yu, Tzu-Jung, et al.
Publicado: (2023)

Physapruin A Induces Reactive Oxygen Species to Trigger Cytoprotective Autophagy of Breast Cancer Cells
por: Yu, Tzu-Jung, et al.
Publicado: (2022)

4β-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G(2)/M arrest
por: Yen, Ching-Yu, et al.
Publicado: (2010)

Identification of Odor Active Compounds in Physalis peruviana L.
por: Majcher, Małgorzata A., et al.
Publicado: (2020)

Quality of Physalis peruviana fruits coated with pectin and pectin reinforced with nanocellulose from P. peruviana calyces
por: Cárdenas-Barboza, Liceth Carolina, et al.
Publicado: (2021)

Development and Characterization of Microsatellite Markers for the Cape Gooseberry Physalis peruviana
por: Simbaqueba, Jaime, et al.
Publicado: (2011)

Acute and Subchronic Toxic Effects of the Fruits of Physalis peruviana L.
por: Perk, Basak Ozlem, et al.
Publicado: (2013)

Ethnotherapeutic Uses and Phytochemical Composition of Physalis peruviana L.: An Overview
por: Kasali, Félicien Mushagalusa, et al.
Publicado: (2021)

Comparative Characterization of the Leaf Tissue of Physalis alkekengi and Physalis peruviana Using RNA-seq and Metabolite Profiling
por: Fukushima, Atsushi, et al.
Publicado: (2016)

Combined Treatment (Ultraviolet-C/Physapruin A) Enhances Antiproliferation and Oxidative-Stress-Associated Mechanism in Oral Cancer Cells
por: Peng, Sheng-Yao, et al.
Publicado: (2022)

The Physalis peruviana leaf transcriptome: assembly, annotation and gene model prediction
por: Garzón-Martínez, Gina A, et al.
Publicado: (2012)

Identification of Immunity Related Genes to Study the Physalis peruviana – Fusarium oxysporum Pathosystem
por: Enciso-Rodríguez, Felix E., et al.
Publicado: (2013)

Extracts of Physalis peruviana Protect Astrocytic Cells Under Oxidative Stress With Rotenone
por: Areiza-Mazo, Natalia, et al.
Publicado: (2018)

Isolation and characterisation of irinans, androstane-type withanolides from Physalis peruviana L.
por: Stein, Annika, et al.
Publicado: (2019)

Dataset on the change of postharvest quality of Physalis peruviana L. as an effect of ethylene inhibitor
por: Mubarok, Syariful, et al.
Publicado: (2019)

Association analysis for disease resistance to Fusarium oxysporum in cape gooseberry (Physalis peruviana L)
por: Osorio-Guarín, Jaime A., et al.
Publicado: (2016)

Rheological, Chemical and Physical Characteristics of Golden Berry (Physalis peruviana L.) after Convective and Microwave Drying
por: Nawirska-Olszańska, Agnieszka, et al.
Publicado: (2017)

Combining transcriptome analysis and GWAS for identification and validation of marker genes in the Physalis peruviana-Fusarium oxysporum pathosystem
por: Garzón-Martínez, Gina A., et al.
Publicado: (2021)

Chemical Characterization, Nutritional and Bioactive Properties of Physalis peruviana Fruit from High Areas of the Atacama Desert
por: Muñoz, Patricio, et al.
Publicado: (2021)

Hypoglycemic, Antihyperglycemic, and Toxic Effects of Physalis peruviana L. Aqueous and Methanolic Leaf Extracts in Wistar Rats
por: Kasali, Félicien Mushagalusa, et al.
Publicado: (2022)

Analysis of Volatile Components of Cape Gooseberry (Physalis peruviana L.) Grown in Turkey by HS-SPME and GC-MS
por: Yilmaztekin, Murat
Publicado: (2014)

Renoprotective Effect of Egyptian Cape Gooseberry Fruit (Physalis peruviana L.) against Acute Renal Injury in Rats
por: Ahmed, Lamiaa Ali
Publicado: (2014)

Association Study Reveals Novel Genes Related to Yield and Quality of Fruit in Cape Gooseberry (Physalis peruviana L.)
por: García-Arias, Francy L., et al.
Publicado: (2018)

Optimization of the genotyping‐by‐sequencing SNP calling for diversity analysis in cape gooseberry (Physalis peruviana L.) and related taxa
por: Enciso-Rodríguez, Felix E., et al.
Publicado: (2020)

Extract of Calyces from Physalis peruviana Reduces Insulin Resistance and Oxidative Stress in Streptozotocin-Induced Diabetic Mice
por: Valderrama, Ivonne Helena, et al.
Publicado: (2022)

Studying the microbiome of suppressive soils against vascular wilt, caused by Fusarium oxysporum in cape gooseberry (Physalis peruviana)
por: Bautista, Daniel, et al.
Publicado: (2023)

Physalis peruviana L. inhibits ovalbumin-induced airway inflammation by attenuating the activation of NF-κB and inflammatory molecules
por: Park, Hyun Ah, et al.
Publicado: (2019)

Effects of moderate high temperature and UV-B on accumulation of withanolides and relative expression of the squalene synthase gene in Physalis peruviana
por: ŞAHİN, Günce, et al.
Publicado: (2020)

Physalis peruviana L. Pulp Prevents Liver Inflammation and Insulin Resistance in Skeletal Muscles of Diet-Induced Obese Mice
por: Pino-de la Fuente, Francisco, et al.
Publicado: (2020)

Matrix Effects of the Hydroethanolic Extract of Calyces of Physalis peruviana L. on Rutin Pharmacokinetics in Wistar Rats Using Population Modeling
por: Domínguez Moré, Gina Paola, et al.
Publicado: (2021)

Effect of Salt Stress on Growth and Metabolite Profiles of Cape Gooseberry (Physalis peruviana L.) along Three Growth Stages
por: Monroy-Velandia, Daissy, et al.
Publicado: (2021)

Cytotoxic and Immunomodulatory Potential Activity of Physalis peruviana Fruit Extracts on Cervical Cancer (HeLa) and Fibroblast (L929) Cells
por: Mier-Giraldo, Helen, et al.
Publicado: (2017)

QTOF-ESI MS Characterization and Antioxidant Activity of Physalis peruviana L. (Cape Gooseberry) Husks and Fruits from Costa Rica
por: Navarro-Hoyos, Mirtha, et al.
Publicado: (2022)

Physalis peruviana-Derived 4β-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo
por: Ye, Zhen-Nan, et al.
Publicado: (2019)

Physalis peruviana L. (Solanaceae) Is Not a Host of Ceratitis capitata (Diptera: Tephritidae): Evidence from Multi-Year Field and Laboratory Studies in Colombia
por: Aluja, Martín, et al.
Publicado: (2019)

Flash vacuum expansion, a low-cost and energy-efficient alternative process to produce high-quality fruit puree: Application to Physalis peruviana
por: Arias, Claudia, et al.
Publicado: (2023)

Withanolide C Inhibits Proliferation of Breast Cancer Cells via Oxidative Stress-Mediated Apoptosis and DNA Damage
por: Yu, Tzu-Jung, et al.
Publicado: (2020)

Effects of carrier agents on powder properties, stability of carotenoids, and encapsulation efficiency of goldenberry (Physalis peruviana L.) powder produced by co-current spray drying
por: Etzbach, Lara, et al.
Publicado: (2020)

Nephroprotective effect of Physalis peruviana L. calyx extract and its butanolic fraction against cadmium chloride toxicity in rats and molecular docking of isolated compounds
por: Soliman, Hesham S. M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_s6o1vgiqupgs1f0jh0l4o36s8m