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Rapid and High-Throughput Evaluation of Diverse Configurations of Engineered Lysins Using the VersaTile Technique
Bacteriophage-encoded lysins are an emerging class of antibacterial enzymes based on peptidoglycan degradation. The modular composition of lysins is a hallmark feature enabling optimization of antibacterial and pharmacological properties by engineering of lysin candidates based on lysin and non-lysi...
Autores principales: | Duyvejonck, Lisa, Gerstmans, Hans, Stock, Michiel, Grimon, Dennis, Lavigne, Rob, Briers, Yves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998686/ https://www.ncbi.nlm.nih.gov/pubmed/33799561 http://dx.doi.org/10.3390/antibiotics10030293 |
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