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Epstein–Barr Virus LMP1 Induces Soluble PD-L1 in Nasopharyngeal Carcinoma

Nasopharyngeal carcinoma (NPC) is an Epstein–Barr virus (EBV)-associated malignancy. The principal oncogene of EBV, latent membrane protein 1 (LMP1), induces the expression of programmed death-ligand 1 (PD-L1), which is an immunosuppressive transmembrane protein and a promising therapeutic target fo...

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Detalles Bibliográficos
Autores principales: Kase, Kina, Kondo, Satoru, Wakisaka, Naohiro, Dochi, Hirotomo, Mizokami, Harue, Kobayashi, Eiji, Kano, Makoto, Komori, Takeshi, Hirai, Nobuyuki, Ueno, Takayoshi, Nakanishi, Yosuke, Hatano, Miyako, Endo, Kazuhira, Moriyama-Kita, Makiko, Sugimoto, Hisashi, Yoshizaki, Tomokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998736/
https://www.ncbi.nlm.nih.gov/pubmed/33804064
http://dx.doi.org/10.3390/microorganisms9030603