Polymorphisms within Autophagy-Related Genes Influence the Risk of Developing Colorectal Cancer: A Meta-Analysis of Four Large Cohorts

SIMPLE SUMMARY: We investigated the influence of autophagy-related variants in modulating colorectal cancer (CRC) risk through a meta-analysis of genome-wide association study (GWAS) data from four large European cohorts. We found that genetic variants within the DAPK2 and ATG5 loci were associated...

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Detalles Bibliográficos
Autores principales: Sainz, Juan, García-Verdejo, Francisco José, Martínez-Bueno, Manuel, Kumar, Abhishek, Sánchez-Maldonado, José Manuel, Díez-Villanueva, Anna, Vodičková, Ludmila, Vymetálková, Veronika, Martin Sánchez, Vicente, Da Silva Filho, Miguel Inacio, Sampaio-Marques, Belém, Brezina, Stefanie, Butterbach, Katja, ter Horst, Rob, Hoffmeister, Michael, Ludovico, Paula, Jurado, Manuel, Li, Yang, Sánchez-Rovira, Pedro, Netea, Mihai G., Gsur, Andrea, Vodička, Pavel, Moreno, Víctor, Hemminki, Kari, Brenner, Hermann, Chang-Claude, Jenny, Försti, Asta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998818/
https://www.ncbi.nlm.nih.gov/pubmed/33809172
http://dx.doi.org/10.3390/cancers13061258

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