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Interleukin-1α Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic Inflammation

Eosinophils contribute to allergic inflammation in asthma in part via elaboration of a complex milieu of soluble mediators. Human bronchial fibroblasts (HBF) respond to stimulation by these mediators by acquiring a pro-inflammatory profile including induction of interleukin 6 (IL6) and IL8. This stu...

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Detalles Bibliográficos
Autores principales: Bernau, Ksenija, Leet, Jonathan P., Floerke, Heather, Bruhn, Ellen M., Noll, Andrea L., McDermott, Ivy S., Esnault, Stephane, Jarjour, Nizar N., Sandbo, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998867/
https://www.ncbi.nlm.nih.gov/pubmed/33801398
http://dx.doi.org/10.3390/cells10030528