Cargando…

3-Hydroxypropane-1,2-Diyl Dipalmitoleate—A Natural Compound with Dual Roles (CB1 Agonist/FAAH1 Blocker) in Inhibiting Ovarian Cancer Cell Line

Though it was once known that upregulated Cannabinoid Receptor (CB1) and downregulated Fatty Acid Amide Hydrolase (FAAH1) are associated with tumour aggressiveness and metastasis, it is now clear that upregulated CB1 levels more than a certain point cause accumulation of ceramide and directs cells t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sathynathan, Christina Vijayaraghavan, Raman, Lakshmi Sundaram, Vajiravelu, Sivamurugan, Kumar, Thirumal D., Panchatcharam, Thyagarajan Sadras, Narasimhan, Gopinathan, Doss, George C. Priya, Krishnan, Mary Elizabeth Gnanambal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998876/ https://www.ncbi.nlm.nih.gov/pubmed/33809034 http://dx.doi.org/10.3390/ph14030255

Ejemplares similares

Structure elucidation and proposed de novo synthesis of an unusual mono-rhamnolipid by Pseudomonas guguanensis from Chennai Port area
por: Ramya Devi, K. C., et al.
Publicado: (2019)

Inhibition of MMP2-PEX by a novel ester of dihydroxy cinnamic and linoleic acid from the seagrass Cymodocea serrulata
por: Christina, V. S., et al.
Publicado: (2021)

Synthesis of Four Enantiomers of (1-Amino-3-Hydroxypropane-1,3-Diyl)Diphosphonic Acid as Diphosphonate Analogues of 4-Hydroxyglutamic Acid
por: Lebelt, Liwia, et al.
Publicado: (2022)

N,N′-(2-Hydroxypropane-1,3-diyl)bis(2-hydroxybenzamide) monohydrate
por: Yebedri, Sihem, et al.
Publicado: (2013)

{5,5′-Dihydroxy-2,2′-[(2-hydroxypropane-1,3-diyl)bis(nitrilomethanylylidene)]diphenolato}nickel(II) dihydrate
por: Datta, Amitabha, et al.
Publicado: (2013)

Expression and localization of CB1R, NAPE-PLD, and FAAH in the vervet monkey nucleus accumbens
por: Kucera, Ryan, et al.
Publicado: (2018)

Is Herd Immunity Against SARS-CoV-2 a Silver Lining?
por: Vignesh, Ramachandran, et al.
Publicado: (2020)

3-Diazo-N-[(2S)-1-hydroxypropan-2-yl]-2-oxopropanamide
por: Chen, Xiao-na, et al.
Publicado: (2011)

4,4′-Bipyridine–2-hydroxypropane-1,2,3-tricarboxylic acid (3/2)
por: Soleimannejad, Janet, et al.
Publicado: (2009)

In Vitro One-Pot 3-Hydroxypropanal Production from Cheap C1 and C2 Compounds
por: Ju, Su-Bin, et al.
Publicado: (2022)

Epigenetic (re)programming of gene expression changes of CB1R and FAAH in the medial prefrontal cortex in response to early life and adolescence stress exposure
por: Demaili, Arijana, et al.
Publicado: (2023)

Strategy for COVID-19 vaccination in India: the country with the second highest population and number of cases
por: Kumar, Velayudhan Mohan, et al.
Publicado: (2021)

2-[4-(2-Hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl]phenol
por: Zhang, Li-Li, et al.
Publicado: (2012)

FAAH inhibitors in the limelight, but regrettably
por: Mallet, Christophe, et al.
Publicado: (2016)

Coupling of CB-2 and CB-1
por: Ansaldo
Publicado: (2003)

Cannabigerol Action at Cannabinoid CB(1) and CB(2) Receptors and at CB(1)–CB(2) Heteroreceptor Complexes
por: Navarro, Gemma, et al.
Publicado: (2018)

Diguanidinium bis(μ-2-hydroxypropane-1,2,3-tricarboxylato)bis[diaquazincate(II)] dihydrate
por: Al-Dajani, Mohammad T. M., et al.
Publicado: (2010)

A catalytically silent FAAH-1 variant drives anandamide transport in neurons
por: Fu, Jin, et al.
Publicado: (2011)

Metabolism and disposition of MM-433593, a selective FAAH-1 inhibitor, in monkeys
por: Banijamali, Ali R, et al.
Publicado: (2014)

FAAH and CNR1 Polymorphisms in the Endocannabinoid System and Alcohol-Related Sleep Quality
por: Soundararajan, Soundarya, et al.
Publicado: (2021)

(S)-1-Hydroxypropan-2-aminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate monohydrate
por: Tang, Xin-Yu, et al.
Publicado: (2008)

FAAH selectively influences placebo effects
por: Peciña, M., et al.
Publicado: (2013)

The endocannabinoid hydrolase FAAH is an allosteric enzyme
por: Dainese, Enrico, et al.
Publicado: (2020)

2-(2-Hydroxypropan-2-yl)-6-(prop-2-ynyloxy)-1-benzofuran-3(2H)-one
por: Kinfe, Henok H., et al.
Publicado: (2012)

Winding of CB-1
por: P. Fabbricatore
Publicado: (2003)

A polymorphism in the gene of the endocannabinoid-degrading enzyme FAAH (FAAH C385A) is associated with emotional–motivational reactivity
por: Conzelmann, Annette, et al.
Publicado: (2012)

(Cyclopentane-1,1-diyl)dimethanol
por: Betz, Richard, et al.
Publicado: (2009)

Cooperative enzymatic control of N-acyl amino acids by PM20D1 and FAAH
por: Kim, Joon T, et al.
Publicado: (2020)

Inversion dimers dominate the crystal packing in the structure of trimethyl citrate (trimethyl 2-hydroxypropane-1,2,3-tricarboxylate)
por: Morjan, Rami Y., et al.
Publicado: (2018)

CB0 is finished machining, and for CB+1 the shell is finished.
por: P. Fabbricatore
Publicado: (2003)

CB-1 after impregnation ready for coupling with CB-2.
por: Ansaldo
Publicado: (2003)

Situation of CB+1/CB+2 mid January 2004
por: Ansaldo
Publicado: (2004)

Cannabinoid CB(1) and CB(2) Receptor Signaling and Bias
por: Ibsen, Mikkel Søes, et al.
Publicado: (2017)

Localization of the cannabinoid CB1 receptor and the 2-AG synthesizing (DAGLα) and degrading (MAGL, FAAH) enzymes in cells expressing the Ca(2+)-binding proteins calbindin, calretinin, and parvalbumin in the adult rat hippocampus
por: Rivera, Patricia, et al.
Publicado: (2014)

Bis(μ-3-carboxy-2-hydroxypropane-1,2-dicarboxylato)bis(diaquazinc)–1,2-bis(pyridin-4-yl)ethene–water (1/1/2)
por: Hwang, In Hong, et al.
Publicado: (2012)

Hydroxonium 1-ammonioethane-1,1-diyldiphosphonate
por: Li, Ming, et al.
Publicado: (2009)

1,1′-(Butane-1,4-diyl)diimidazolium dinitrate
por: Jin, Shouwen, et al.
Publicado: (2007)

3-Oxapentane-1,5-diyl dicarbamate
por: Li, Zhi
Publicado: (2012)

(R)-1,1′-Binaphthalene-2,2′-diyl dicinnamate
por: Weng, Wen, et al.
Publicado: (2008)

1,1′-Binaphthalene-2,2′-diyl hydrogen phosphate
por: Nayak, Susanta K., et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_en8j0aulqbem6jop9d60716ug3