Formulation, Stability, Pharmacokinetic, and Modeling Studies for Tests of Synergistic Combinations of Orally Available Approved Drugs against Ebola Virus In Vivo

Outbreaks of Ebola ebolavirus (EBOV) have been associated with high morbidity and mortality. Milestones have been reached recently in the management of EBOV disease (EVD) with licensure of an EBOV vaccine and two monoclonal antibody therapies. However, neither vaccines nor therapies are available fo...

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Detalles Bibliográficos
Autores principales: Finch, Courtney L., Dyall, Julie, Xu, Shuang, Nelson, Elizabeth A., Postnikova, Elena, Liang, Janie Y., Zhou, Huanying, DeWald, Lisa Evans, Thomas, Craig J., Wang, Amy, Xu, Xin, Hughes, Emma, Morris, Patrick J., Mirsalis, Jon C., Nguyen, Linh H., Arolfo, Maria P., Koci, Bryan, Holbrook, Michael R., Hensley, Lisa E., Jahrling, Peter B., Schmaljohn, Connie, Johansen, Lisa M., Olinger, Gene G., Schiffer, Joshua T., White, Judith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998926/
https://www.ncbi.nlm.nih.gov/pubmed/33801811
http://dx.doi.org/10.3390/microorganisms9030566

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