Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the Sod1 Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disease arising from the combined degeneration of upper motor neurons (UMN) in the motor cortex, and lower motor neurons (LMN) in the brainstem and spinal cord. This dual impairment raises two major questions: (i) are t...

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Detalles Bibliográficos
Autores principales: Marques, Christine, Burg, Thibaut, Scekic-Zahirovic, Jelena, Fischer, Mathieu, Rouaux, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7998935/
https://www.ncbi.nlm.nih.gov/pubmed/33805792
http://dx.doi.org/10.3390/brainsci11030369

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