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Role of Vitamin D in the Metabolic Syndrome

The prevalence of hypovitaminosis D has risen in developed countries over the past few years in association with lifestyle changes and an increase in unhealthy habits. Vitamin D deficiency has been implicated in various diseases, including metabolic syndrome (MetS), which is clinically defined by a...

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Autores principales: Melguizo-Rodríguez, Lucía, Costela-Ruiz, Víctor J., García-Recio, Enrique, De Luna-Bertos, Elvira, Ruiz, Concepción, Illescas-Montes, Rebeca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999005/
https://www.ncbi.nlm.nih.gov/pubmed/33802330
http://dx.doi.org/10.3390/nu13030830
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author Melguizo-Rodríguez, Lucía
Costela-Ruiz, Víctor J.
García-Recio, Enrique
De Luna-Bertos, Elvira
Ruiz, Concepción
Illescas-Montes, Rebeca
author_facet Melguizo-Rodríguez, Lucía
Costela-Ruiz, Víctor J.
García-Recio, Enrique
De Luna-Bertos, Elvira
Ruiz, Concepción
Illescas-Montes, Rebeca
author_sort Melguizo-Rodríguez, Lucía
collection PubMed
description The prevalence of hypovitaminosis D has risen in developed countries over the past few years in association with lifestyle changes and an increase in unhealthy habits. Vitamin D deficiency has been implicated in various diseases, including metabolic syndrome (MetS), which is clinically defined by a set of metabolic and vascular disorders. The objective of this study was to review scientific evidence on the relationship between MetS and vitamin D deficiency to support the development of prevention strategies and health education programs. An inverse relationship has been reported between plasma vitamin D concentrations and the features that define MetS, i.e., elevated serum concentrations of glucose, total cholesterol, low-density lipoproteins, triglycerides, glycosylated hemoglobin, and a high body mass index. Numerous studies have described the benefits of vitamin D supplementation to improve outcomes in individuals with MetS. Interventions to maintain optimal vitamin D concentrations are proposed as a preventive strategy against MetS.
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spelling pubmed-79990052021-03-28 Role of Vitamin D in the Metabolic Syndrome Melguizo-Rodríguez, Lucía Costela-Ruiz, Víctor J. García-Recio, Enrique De Luna-Bertos, Elvira Ruiz, Concepción Illescas-Montes, Rebeca Nutrients Review The prevalence of hypovitaminosis D has risen in developed countries over the past few years in association with lifestyle changes and an increase in unhealthy habits. Vitamin D deficiency has been implicated in various diseases, including metabolic syndrome (MetS), which is clinically defined by a set of metabolic and vascular disorders. The objective of this study was to review scientific evidence on the relationship between MetS and vitamin D deficiency to support the development of prevention strategies and health education programs. An inverse relationship has been reported between plasma vitamin D concentrations and the features that define MetS, i.e., elevated serum concentrations of glucose, total cholesterol, low-density lipoproteins, triglycerides, glycosylated hemoglobin, and a high body mass index. Numerous studies have described the benefits of vitamin D supplementation to improve outcomes in individuals with MetS. Interventions to maintain optimal vitamin D concentrations are proposed as a preventive strategy against MetS. MDPI 2021-03-03 /pmc/articles/PMC7999005/ /pubmed/33802330 http://dx.doi.org/10.3390/nu13030830 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Review
Melguizo-Rodríguez, Lucía
Costela-Ruiz, Víctor J.
García-Recio, Enrique
De Luna-Bertos, Elvira
Ruiz, Concepción
Illescas-Montes, Rebeca
Role of Vitamin D in the Metabolic Syndrome
title Role of Vitamin D in the Metabolic Syndrome
title_full Role of Vitamin D in the Metabolic Syndrome
title_fullStr Role of Vitamin D in the Metabolic Syndrome
title_full_unstemmed Role of Vitamin D in the Metabolic Syndrome
title_short Role of Vitamin D in the Metabolic Syndrome
title_sort role of vitamin d in the metabolic syndrome
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999005/
https://www.ncbi.nlm.nih.gov/pubmed/33802330
http://dx.doi.org/10.3390/nu13030830
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