Cargando…
Role of Vitamin D in the Metabolic Syndrome
The prevalence of hypovitaminosis D has risen in developed countries over the past few years in association with lifestyle changes and an increase in unhealthy habits. Vitamin D deficiency has been implicated in various diseases, including metabolic syndrome (MetS), which is clinically defined by a...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999005/ https://www.ncbi.nlm.nih.gov/pubmed/33802330 http://dx.doi.org/10.3390/nu13030830 |
_version_ | 1783670682990673920 |
---|---|
author | Melguizo-Rodríguez, Lucía Costela-Ruiz, Víctor J. García-Recio, Enrique De Luna-Bertos, Elvira Ruiz, Concepción Illescas-Montes, Rebeca |
author_facet | Melguizo-Rodríguez, Lucía Costela-Ruiz, Víctor J. García-Recio, Enrique De Luna-Bertos, Elvira Ruiz, Concepción Illescas-Montes, Rebeca |
author_sort | Melguizo-Rodríguez, Lucía |
collection | PubMed |
description | The prevalence of hypovitaminosis D has risen in developed countries over the past few years in association with lifestyle changes and an increase in unhealthy habits. Vitamin D deficiency has been implicated in various diseases, including metabolic syndrome (MetS), which is clinically defined by a set of metabolic and vascular disorders. The objective of this study was to review scientific evidence on the relationship between MetS and vitamin D deficiency to support the development of prevention strategies and health education programs. An inverse relationship has been reported between plasma vitamin D concentrations and the features that define MetS, i.e., elevated serum concentrations of glucose, total cholesterol, low-density lipoproteins, triglycerides, glycosylated hemoglobin, and a high body mass index. Numerous studies have described the benefits of vitamin D supplementation to improve outcomes in individuals with MetS. Interventions to maintain optimal vitamin D concentrations are proposed as a preventive strategy against MetS. |
format | Online Article Text |
id | pubmed-7999005 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79990052021-03-28 Role of Vitamin D in the Metabolic Syndrome Melguizo-Rodríguez, Lucía Costela-Ruiz, Víctor J. García-Recio, Enrique De Luna-Bertos, Elvira Ruiz, Concepción Illescas-Montes, Rebeca Nutrients Review The prevalence of hypovitaminosis D has risen in developed countries over the past few years in association with lifestyle changes and an increase in unhealthy habits. Vitamin D deficiency has been implicated in various diseases, including metabolic syndrome (MetS), which is clinically defined by a set of metabolic and vascular disorders. The objective of this study was to review scientific evidence on the relationship between MetS and vitamin D deficiency to support the development of prevention strategies and health education programs. An inverse relationship has been reported between plasma vitamin D concentrations and the features that define MetS, i.e., elevated serum concentrations of glucose, total cholesterol, low-density lipoproteins, triglycerides, glycosylated hemoglobin, and a high body mass index. Numerous studies have described the benefits of vitamin D supplementation to improve outcomes in individuals with MetS. Interventions to maintain optimal vitamin D concentrations are proposed as a preventive strategy against MetS. MDPI 2021-03-03 /pmc/articles/PMC7999005/ /pubmed/33802330 http://dx.doi.org/10.3390/nu13030830 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Review Melguizo-Rodríguez, Lucía Costela-Ruiz, Víctor J. García-Recio, Enrique De Luna-Bertos, Elvira Ruiz, Concepción Illescas-Montes, Rebeca Role of Vitamin D in the Metabolic Syndrome |
title | Role of Vitamin D in the Metabolic Syndrome |
title_full | Role of Vitamin D in the Metabolic Syndrome |
title_fullStr | Role of Vitamin D in the Metabolic Syndrome |
title_full_unstemmed | Role of Vitamin D in the Metabolic Syndrome |
title_short | Role of Vitamin D in the Metabolic Syndrome |
title_sort | role of vitamin d in the metabolic syndrome |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999005/ https://www.ncbi.nlm.nih.gov/pubmed/33802330 http://dx.doi.org/10.3390/nu13030830 |
work_keys_str_mv | AT melguizorodriguezlucia roleofvitamindinthemetabolicsyndrome AT costelaruizvictorj roleofvitamindinthemetabolicsyndrome AT garciarecioenrique roleofvitamindinthemetabolicsyndrome AT delunabertoselvira roleofvitamindinthemetabolicsyndrome AT ruizconcepcion roleofvitamindinthemetabolicsyndrome AT illescasmontesrebeca roleofvitamindinthemetabolicsyndrome |