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EGFRvIII Promotes Cell Survival during Endoplasmic Reticulum Stress through a Reticulocalbin 1-Dependent Mechanism

SIMPLE SUMMARY: A key molecule, EGFRvIII has been shown to provide several growth advantages for brain tumors. However, we have found a new mechanism in which the EGFRvIII provides increased survival to brain cancer cells when under sub-optimal conditions. Specifically, we have found that the EGFRvI...

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Detalles Bibliográficos
Autores principales: Gomez, Juliana, Areeb, Zammam, Stuart, Sarah F., Nguyen, Hong P. T., Paradiso, Lucia, Zulkifli, Ahmad, Madan, Sonakshi, Rajagopal, Vijay, Montgomery, Magdalene K., Gan, Hui K., Scott, Andrew M., Jones, Jordan, Kaye, Andrew H., Morokoff, Andrew P., Luwor, Rodney B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999088/
https://www.ncbi.nlm.nih.gov/pubmed/33801941
http://dx.doi.org/10.3390/cancers13061198