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EGFRvIII Promotes Cell Survival during Endoplasmic Reticulum Stress through a Reticulocalbin 1-Dependent Mechanism
SIMPLE SUMMARY: A key molecule, EGFRvIII has been shown to provide several growth advantages for brain tumors. However, we have found a new mechanism in which the EGFRvIII provides increased survival to brain cancer cells when under sub-optimal conditions. Specifically, we have found that the EGFRvI...
Autores principales: | Gomez, Juliana, Areeb, Zammam, Stuart, Sarah F., Nguyen, Hong P. T., Paradiso, Lucia, Zulkifli, Ahmad, Madan, Sonakshi, Rajagopal, Vijay, Montgomery, Magdalene K., Gan, Hui K., Scott, Andrew M., Jones, Jordan, Kaye, Andrew H., Morokoff, Andrew P., Luwor, Rodney B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999088/ https://www.ncbi.nlm.nih.gov/pubmed/33801941 http://dx.doi.org/10.3390/cancers13061198 |
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