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p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair

SIMPLE SUMMARY: Given their high degree of identity and even greater similarity at the amino acid level, Kat3 coactivators, CBP (Kat3A) and p300 (Kat3B), have long been considered redundant. We describe the generation of novel p300 S89A knock-in mice carrying a single site directed amino acid mutati...

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Detalles Bibliográficos
Autores principales: Lai, Keane K. Y., Hu, Xiaohui, Chosa, Keisuke, Nguyen, Cu, Lin, David P., Lai, Keith K., Kato, Nobuo, Higuchi, Yusuke, Highlander, Sarah K., Melendez, Elizabeth, Eriguchi, Yoshihiro, Fueger, Patrick T., Ouellette, Andre J., Chimge, Nyam-Osor, Ono, Masaya, Kahn, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999107/
https://www.ncbi.nlm.nih.gov/pubmed/33799418
http://dx.doi.org/10.3390/cancers13061288