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p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair
SIMPLE SUMMARY: Given their high degree of identity and even greater similarity at the amino acid level, Kat3 coactivators, CBP (Kat3A) and p300 (Kat3B), have long been considered redundant. We describe the generation of novel p300 S89A knock-in mice carrying a single site directed amino acid mutati...
Autores principales: | Lai, Keane K. Y., Hu, Xiaohui, Chosa, Keisuke, Nguyen, Cu, Lin, David P., Lai, Keith K., Kato, Nobuo, Higuchi, Yusuke, Highlander, Sarah K., Melendez, Elizabeth, Eriguchi, Yoshihiro, Fueger, Patrick T., Ouellette, Andre J., Chimge, Nyam-Osor, Ono, Masaya, Kahn, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999107/ https://www.ncbi.nlm.nih.gov/pubmed/33799418 http://dx.doi.org/10.3390/cancers13061288 |
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