Implication of EZH2 in the Pro-Proliferative and Apoptosis-Resistant Phenotype of Pulmonary Artery Smooth Muscle Cells in PAH: A Transcriptomic and Proteomic Approach

Pulmonary arterial hypertension (PAH) is a progressive disorder characterized by a sustained elevation of pulmonary artery (PA) pressure, right ventricular failure, and premature death. Enhanced proliferation and resistance to apoptosis (as seen in cancer cells) of PA smooth muscle cells (PASMCs) is...

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Detalles Bibliográficos
Autores principales: Habbout, Karima, Omura, Junichi, Awada, Charifa, Bourgeois, Alice, Grobs, Yann, Krishna, Vinod, Breuils-Bonnet, Sandra, Tremblay, Eve, Mkannez, Ghada, Martineau, Sandra, Nadeau, Valérie, Roux-Dalvai, Florence, Orcholski, Mark, Jeyaseelan, Jey, Gutstein, David, Potus, François, Provencher, Steeve, Bonnet, Sébastien, Paulin, Roxane, Boucherat, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999120/
https://www.ncbi.nlm.nih.gov/pubmed/33803922
http://dx.doi.org/10.3390/ijms22062957

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