In Ovarian Cancer Multicellular Spheroids, Platelet Releasate Promotes Growth, Expansion of ALDH+ and CD133+ Cancer Stem Cells, and Protection against the Cytotoxic Effects of Cisplatin, Carboplatin and Paclitaxel

A high platelet count is associated with a poor prognosis in ovarian cancer (OvCa). Despite good clinical responses with platinating agents in combination with taxanes, numerous OvCa patients relapse due to chemotherapy resistance. Here, we report that treatment of OvCa cells A2780, OVCAR5 and MDAH...

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Detalles Bibliográficos
Autores principales: Casagrande, Naike, Borghese, Cinzia, Agostini, Francesco, Durante, Cristina, Mazzucato, Mario, Colombatti, Alfonso, Aldinucci, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999151/
https://www.ncbi.nlm.nih.gov/pubmed/33809553
http://dx.doi.org/10.3390/ijms22063019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999151/
https://www.ncbi.nlm.nih.gov/pubmed/33809553
http://dx.doi.org/10.3390/ijms22063019

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