HCV Core/NS3 Protein Immunization with “N-Terminal Heat Shock gp96 Protein (rNT (gp96))” Induced Strong and Sustained Th1-Type Cytokines in Immunized Mice

Feeble cellular responses induced by T cell-based vaccines are a major challenge for the development of an effective vaccine against Hepatitis C virus (HCV) infection. To address this challenge, the potential of N-terminal fragment of gp96 heat shock protein (rNT (gp96) as an adjuvant was evaluated...

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Detalles Bibliográficos
Autores principales: Hajikhezri, Zamaneh, Roohvand, Farzin, Maleki, Monireh, Shahmahmoodi, Shohreh, Amirzargar, Ali Akbar, Keshavarz, Abolfazl, Seyed, Negar, Farahmand, Mohammad, Samimi-Rad, Katayoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999198/
https://www.ncbi.nlm.nih.gov/pubmed/33802466
http://dx.doi.org/10.3390/vaccines9030215

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